The Magpies’ under-19s return to the competition in 2025/26, which will mirror the new format of the UEFA Champions League with an initial 36-team league phase.
They will, however, play just the first six parallel fixtures in the Youth League league phase, in contrast to the eight matches contested in the Champions League.
Newcastle's schedule can be found below, with full fixture details to be announced on newcastleunited.com in due course.
FC Barcelona
Union Saint-Gilloise
Benfica
Athletic Club
Olympique Marseille
Bayer Leverkusen
The top 22 finishers in the league phase will progress into the knockout rounds, which will begin in February 2026 and will also include ten qualifiers from the tournament’s separate domestic champions path.
Academy Director Steve Harper said: "The UEFA Youth League is a brilliant benchmark for our young players, not just in terms of footballing ability but in how they prepare, travel and represent the club on a European stage.
"It's a chance to test themselves against some of the best Academies in the world and we've seen first-hand how those experiences accelerate growth both on and off the pitch.
"We're excited by the challenge ahead and confident our lads will embrace every moment of the journey."