The young Magpies, led by head coach Chris Moore, were awarded a penalty in the opening stages after a Trialist was fouled inside the box but his resulting spot-kick was held by the Blackpool goalkeeper, who guessed the correct way to deny the teenage forward.
Michael Mills, who joined the Magpies' youth set-up from Port Vale in the summer of 2023, was withdrawn towards the half-hour due to injury before the hosts were fortunate to remain on level terms towards the break after the Blackpool centre-forward's header struck the crossbar.
After nine changes were made before the restart, teenage striker Kacey Wooster went close to opening the scoring in the early stages of the second-half as the 17-year-old combined neatly with Sam Alabi before his resulting shot from the edge of the box was beaten away by the Tangerines goalkeeper.
Sammy Pinnington, who joined Newcastle from Luton Town in the summer of 2023, went narrowly close to breaking the deadlock after latching onto a teasing cross from the left flank at the back post but his sliding first-time effort struck the side-netting.
Wooster, who scored eight goals in the Under-18 Premier League North last season, created another opportunity in front of goal after connecting with Pinnington's teasing pass inside the penalty area but his first-time shot at goal was saved.
Newcastle's clean sheet hopes were almost dashed in the final minutes of the friendly as an in-swinging corner struck the top of the crossbar before the ball bounced clear to safety, ensuring a stalemate on Tyneside.
Newcastle United Under-18s: Tyler Jones (Will Anderson 46), Ezra Tika-Lemba (Jack Patterson 46), Thomas Old (Henry Johnson 46), Aaron Epia (Jake Durrant 46), Noah Morgan (Trialist 46), Jude Cogdon (Sam Alabi 46), Kayden Lucas (Mason Miley 46), Alex O'Donovan (Jude Cogdon 69), Ethan Ndiweni (Sammy Pinnington 46), Michael Mills (Mohamed Waddani 27), Trialist (Kacey Wooster 46).